| 刘晓霞,吴思敏,孙秉珍,楚晓丽.中医药及中西医结合治疗亚急性甲状腺炎的系统评价再评价[J].,2025,34(1):93-102 |
| 中医药及中西医结合治疗亚急性甲状腺炎的系统评价再评价 |
| Tiaditional Chinese Medicine and Integrated Traditional Chinese and Westen Medicine in the Treatment of Subacute Thyroiditis: An Overview of Systematic Reviews |
| 投稿时间：2024-04-01 |
| DOI： |
| 中文关键词: 亚急性甲状腺炎 中医药 中西医结合 系统评价再评价 |
| 英文关键词: Subacute Thyroiditis Traditional Chinese Medicine C ombination of Chinese and Western Medicine Overview of Systematic Review |
| 基金项目:陕西省杰出青年科学基金（编号：2023 - JC - JQ - 11) ; 广州市重点研发计划（编号：202206010101) 。 |
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| 中文摘要: |
| 目的：评价中医药及中西医结合治疗亚急性甲状腺炎的系统评价/Meta 分析的方法学质量和结局指标。方法：制定纳排标准，电子检索Pubmed、Embase、Cohraue Librsury、中国知网（CNKI）、中国生物医学文献数据库（CBM）、维普（VIP）、万方（WF）数据库及手工检索，筛选出中医药治疗亚急性甲状腺炎的系统评价/Meta 分析，检索时间为建库至2024月1月18日。由2名研究者进行文献筛选、信息提取，采用PRISMA 2020声明、AMSTAR2工具、CRADE 分级评价纳人研究的报告质量、方法学质量和结局指标的证据质量。结果：共纳人15个系统评价、PRISMA得分≤15分有！
篇，存在相对严重的信息缺陷，>15分≤21分有12篇，报告存在一定缺陷，>21分有2篇，报告相对完整。采用 AM-STAR2工具评价方法学质量提示15篇文献均为板低质量，主要是未提及前期方案及未提供排除文献清单导致关键条目能失。CRADE分级结果显示，在15篇文献的7！个结局指标中，2个为中级证据，26个为低级证据，43个为饭低级证据。结论：中医药及中西医结合治疗亚急性甲状腺炎显示有效，可以减轻思者疼痛、缩短退热时间，降低复发率。然而中医药及中西医结合治疗亚急性甲状腺炎的系统评价报告质量大部分存在一定缺陷，方法学质量方面均为板低质量，结局指标证据质量大部分不高。未来仍需进行更多高质量的临床研究，为中药治疗亚甲炎提供高级别的循证证据。 |
| 英文摘要: |
| Objective To evaluate the methodological quality and outcome indicators of systematie evaluation/ meta - analysia of Chinese medicine and integrated traditional chinese and westen medicine in the treatment of subacute thyroiditis. Methods Numerical criteria were developed, and electronic searches of Pubmed, Embase, Cochrane Library, China Knowledge (CNKI) , China Biomedie-al Literature Database (CBM), Vip (VIP) , Wanfang (WF) databases and manual searches were perforned to sereen out systematie evaluations/Meta - analyses of TCM treatments for subacute thymiditis, with the search time from the construction of the database to January 18, 2024. Literature screening and infonnation extraction were perfored by 2 investigators, and PRISMA 2020 statement, AMSTAR 2 tool, and GRADE grading were used to evaluate the quality of reporting, methodological quality, and quality of evidence for outcome indicators of the included studies. Results A total of 15 systematic evaluations were included, with 1 artiele with a PRIS.
MA score ≤15 with relatively severe information deficiencies, 12 articles with > 15 €21 with some reporting deficiencies, and 2 arti-des with >21 with relatively complete reporting. Evaluation of methodological quality using the AMSTAR 2 tool suggested that all 15 papers were of very low quality, mainly due to the absence of key entries caused by the lack of mention of prior protocols and the failure to provide a list of excluded papers. GRADE grading showed that of the 71 outeome indicators in the 15 papers, 2 were of intermediate level of evidence, 26 were of low level of evidence, and 43 were of very low level of evidence. Conclusion TCM and integrated traditional chinese and western medicine treatment of SAT was shown to be elfective in reducing patients pain, shortening the time of fever
reduetion, and decreasing the recurrence rate. However, the quality of most of the systematic evaluation reports on TCM and integrated traditional chinese and western medieine treatment of SAT has some deficiencies, with all of them being of very low quality in terms of methodologieal quality, and most of the evidence on outcome indicators being of low quality. More high - quality elinical studies are
aill needed in the future to provide high - level evidence - based eridence for TCM treatment of SAT. |
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