文章摘要
李诚丛,高香奇,周星.黎药复体力汤抗疲劳和增强免疫力功能研究[J].,2017,(05):60-62
黎药复体力汤抗疲劳和增强免疫力功能研究
Study on the Anti-Fatigue and Immunity-Enhancing Effect of Recovery Physical Decoction from Hainan Li-Nationality Herbal
  
DOI:
中文关键词: 【关键词】海南黎药  复体力汤  抗疲劳功能  增强免疫力功能
英文关键词: Keywords:HainanLi-nationalityHerbal  RecoveryPhysicalDecoction  Anti-FatigueEffect  ImmuneFunction
基金项目:海南省中药现代化专项(琼科函[2011]261号)。
作者单位E-mail
李诚丛,高香奇,周星 海南省药物研究所 176009938@qq.com 
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中文摘要:
      【摘 要】目的:研究海南黎药复体力汤对运动小鼠抗疲劳和增强免疫力作用,为药物开发提参考依据。方法:使用小鼠为实验对象进行海南黎药复体力汤抗疲劳和增强免疫力试验。结果:抗疲劳试验中,高剂量组(30g/kg·bw) 小鼠游泳至力竭的时间、小鼠肝组织中SOD的活性与对照组比较,均有明显延长或增加(P<0.05),MDA浓度显著减少(P<0.01);增强免疫力试验中,高剂量组(30g/kg·bw)能极显著提高小鼠迟发型变态反应、conA诱导小鼠淋巴细胞转化能力、碳廓清能力和巨噬细胞吞噬鸡红细胞能力(P<0.01)。结论:海南黎药复体力汤具有抗疲劳和增强免疫力的效果。
英文摘要:
      Abstract:ObjectiveTostudytheanti-fatigueandimmunity-enhancingeffectofrecoveryphysicaldecoctionfromHainanLi-nationalityherbalinmice,andtoprovidereferencesfordrugdevelopment.MethodsTheanti-fatigueandimmunity-enhancingtestofrecoveryphysicaldecoctionfromHainanLi-nationalityherbalwereperformedinmice.ResultsIntheanti-fatiguetest,ascomparedwiththecontrolgroup,HainanLi-nationalityherbalatdoseof30g/kg·bwcouldsignificantlyprolongtimethatthemicespentintryingtoswimtoexhaustandsignificantlyincreasetheactivityofSODinthelivertissue(P<0.05),couldsignificantlydecreasetheconcentrationofMDA(P<0.01).Intheenhancedimmunitytest,ascomparedwiththecontrolgroup,HainanLi-nationalityherbalatdoseof30g/kg·bwcouldmarkedlyenhancetheDTHinmice,thelymphocytetransformationcapacityinducedbyconAinmice,thecarbonclearanceabilityandmac rophagephagocytosisofchickenredbloodcellcapacity(P<0.01).ConclusionInourtestcondition,theanti-fatigueeffectofrecoveryphysicaldecoctionfromHainanLi-nationalityherbalisverysignificant,anditcouldenhancetheimmunefunctioninmice.
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